Process Development

OUR FOCUS IN PROCESS DEVELOPMENT IS ON E. COLI AND PICHIA PRODUCTION TECHNOLOGY

Solutions for meeting Large-Scale Needs

With a roster of over 60 completed projects, Richter-Helm possesses extensive experience in developing and optimizing processes for producing recombinant proteins, plasmid DNA, and vaccines.

Our focus is on E.coli and Pichia production technology. Whether the starting point is the cDNA sequence of your target molecule or a preliminary small-scale process, we reliably carry your project to fruition by implementing large-scale, GMP-compliant manufacture. Interdisciplinary teams comprising experts on process development, analytics, and large-volume production ensure smooth scale-up. Small-scale process characterization and validation support round out our capabilities.

Our focus is on E.coli and Pichia production technology. Whether the starting point is the cDNA sequence of your target molecule or a preliminary small-scale process, we reliably carry your project to fruition by implementing large-scale, GMP-compliant manufacture. Interdisciplinary teams comprising experts on process development, analytics, and large-volume production ensure smooth scale-up. Small-scale process characterization and validation support round out our capabilities.

strain and fermentation development services

We make available our considerable expertise on developing strains based on E.coli host systems to produce peptides, proteins (soluble and insoluble), plasmid DNA products, and vaccines. The USP development capabilities at Richter-Helm BioLogics include the full range of leading-edge fermentation strategies for batch and fed-batch concepts based on microbial hosts like E.coli and yeast.

Downstream process development service

We can adjust and fine-tune the steps of downstream process development to meet your needs. This includes complete DSP development from scratch and/or DSP adaptation and optimization studies.

process characterization
services

Process characterization is essential for generating detailed knowledge and in-depth understanding of products and processes.